A mother and her children make palm oil in Meliandou, a village in southeast Guinea believed to be the location of the first known case of Ebola in the West Africa Ebola outbreak. Picture taken February 4, 2015.
"The young girl who was hospitalized at the Ebola treatment centre in Nzerekore is dead," said Fode Tass Sylla, spokesman for the centre that coordinates Guinea's fight against the virus.
Three others have died of the virus since Feb. 29. Health workers on Saturday also stepped up efforts to trace anyone who could have come into contact with the family.
The world's worst recorded Ebola epidemic is believed to have started in Guinea and killed about 2,500 people there by December last year, at which point the U.N. World Health Organization (WHO) said it was no longer actively transmitted.
Fourth person dies of Ebola in latest flare up in Guinea
Reporting by Saliou Samb; Writing by Matthew Mpoke Bigg; Editing by David Gregorio)